Endocrine Abstracts

Introduction: Struma ovarii is a rare condition which elicited considerable interest because of its many unique features like its relationship to teratoma and differentiated thyroid cancer. The most common thyroid carcinomas to arise in struma ovarii are papillary and follicular.Objectives: We describe two patients with differentiated thyroid carcinoma originating from malignant struma ovarii.Results: Our index patient is a 32-year...

Introduction: Brown tumors are rare, destructive, osteolytic bone lesions, occurring in advanced stages of hyperparathyroidism, due to increased osteoclastic activity.Case report: A 25-year-old woman presented with recent, intractable pain on the right shoulder and with hypercalcemia (Ca, 3.93 mmol/l) related to severe primary hyperparathyroidism (PTH, 494 pg/ml). Multiple osteolytic lesions, detected on the upper extremity of the right humerus, distal r...

Introduction: Testicular morphology and immunohistochemistry have never been reported in genetically documented adult patients with 5α-reductase type 2 deficiency (5α-R2 deficiency).Case report: We describe the testicular histopathology of a 17-year-old XY female with primary amenorrhea, failure of pubertal breast development, virilization, clitoromegaly, and bilateral cryptorchidism (testes located in the inguinal canals). The diagnosis of 5&#...

Objectives: Metabolic syndrome, especially obesity and diabetes are associated and responsible for a depressive psychological status. Meanwhile, antidepressors are responsible for metabolic disturbances, such as insulin resistance. The study aims to determine predictive factors of response to antidepressant pharmacotherapy in patients with metabolic syndrome.Materials and methods: A retrospective study conducted in Institute Parhon’s Department for ...